LYLAB

September 2024

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• Lizz Maurais and Rashmi Dahiya attended the 2024 FASEB Consequences of Aneuploidy meeting in Melbourne, Florida and gave wonderful poster/talk presentations on their unpublished work. Great job Lizz and Rashmi!

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August 2024

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• Justin Engel's paper identifying the Fanconi anemia pathway as a source of mitotic chromosome shattering is now published in Cell. Congrats Justin!

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July 2024

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• Qing Hu's paper on how the NHEJ pathway repairs fragmented chromosomes from micronuclei is now published in Nature Communications. Congrats Qing!

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• Congrats to Justin Engel for receiving the NIH Ruth L. Kirschstein Predoctoral National Research Service Award from the National Cancer Institute. Justin also presented a poster at the FASEB Genetic Recombination and Genome Rearrangements meeting in Tucson, Arizona.

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• Brittiny Dhital is awarded a CPRIT Postdoctoral Training Grant Fellowship. Congrats Brittiny!

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June 2024

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• Ahyeon Ko joins the lab as a research technician/lab manager. Welcome Ahyeon!

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April 2024

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• The lab received a 5-year R01 grant from the NIH National Cancer Institute! Thanks for the support!​

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• Our grant from The Welch Foundation has been renewed for another 3 years. Thanks for the continued support!

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• Brittiny Dhital joins the lab as a postdoctoral fellow. Welcome Brittiny!​

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March 2024

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• Justin Engel presented a talk at the 2024 Gordon Research Conference on DNA Damage, Mutation, and Cancer in Ventura, California. Great job Justin!

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January 2024

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• Welcome to Bing-Huan "Nemo" Wu, who joined the lab as a graduate student! Nemo will be part of the Genetics, Development, and Disease Ph.D. program.

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November 2023

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• Alice Mazzagatti and Justin Engel's review on chromothripsis is now published in Molecular Cell. Congrats Alice and Justin!  

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October 2023

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• Congrats to Justin Engel for winning a "Best Poster" award at the UTSW Cancer Biology Retreat!

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August 2023

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• Qing Hu's pre-print on how shattered chromosomes from micronuclei undergo complex rearrangements via NHEJ is posted on bioRxiv. Congrats Qing!

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July 2023

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• Amanda Mennie joins the lab as a postdoctoral fellow. Welcome Amanda!

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June 2023

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• Lizz Maurais received an F31 Ruth L. Kirschstein Predoctoral National Research Service Award from the NIH National Cancer Institute. Congrats Lizz!

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• Rashmi Dahiya presents a poster at the AACR Special Conference on Advances in Kidney Cancer Research meeting held in Austin, Texas. Great job Rashmi!

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• Welcome to our two summer undergraduate fellows AJ Murphy from Brown University and Marisa Albarran from Vanderbilt University! AJ is part of the UTSW SURF Program, and Marisa is part of the UTSW SURISKD Program.

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May 2023

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• Yu-Fen Lin's paper on how shattered chromosomes from micronuclei spatially cluster through the CIP2A-TOPBP1 complex is now published in Nature! This is the first research paper from the lab. Congrats Yu-Fen and team!

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• Congrats to Justin Engel for passing his qualifying exam! Way to go Justin!​​

 

December 2022

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• The lab says farewell to postdoc Jacob Sanders, who is joining the Department of Biochemistry & Cellular and Molecular Biology at the University of Tennessee Knoxville as a lecturer. Good luck Jacob!

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November 2022

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• Kidist Woldehawariat joins the lab as a Research Technician. Welcome Kidist!

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• Check out Yu-Fen and Qing's method paper on how to induce chromosome-specific micronuclei and chromothripsis, now out in Methods in Cell Biology! 

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October 2022

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• The lab visited San Antonio for the inaugural Texas Conference on Genome Repair. Qing an​d Yu-Fen both presented beautiful posters!

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August 2022

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• The lab received a 5-year NIGMS MIRA grant to study micronuclei-driven genomic instability and a 4-year Department of Defense award (as part of the Academy of Kidney Cancer Investigators) to study the development of clear cell renal cell carcinoma. Thanks for supporting our research!

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• The lab says farewell to Alison Guyer, who is heading off to graduate school at the University of Pittsburgh. Good luck Alison!

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July 2022

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• Yu-Fen's pre-print (and the first paper from the lab!) on how fragmented chromosomes from micronuclei cluster during mitosis is posted on bioRxiv! 

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• The lab received 1-year Development Research Program award from the UTSW Kidney SPORE. Thanks for the support!​

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June 2022

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• The lab received the 2022 Haberecht Wildhare-Idea Research Grant from UTSW. Thanks for the support!

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May 2022

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• Lizz Maurais passed her qualifying exam! Congrats Lizz!

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March 2022

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• The lab received a 1-year American Cancer Society – Institutional Research Grant from the UTSW Harold C. Simmons Comprehensive Cancer Center.

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• Rashmi and Qing's review article on mechanisms that cause genomic rearrangements is now out in Seminars in Cell and Developmental Biology. Congrats Rashmi and Qing!

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December 2021

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• Justin Engel joins the lab as a graduate student. Welcome Justin!​

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July 2021

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• Alice Mazzagatti joins the lab as a postdoctoral fellow. Welcome Alice!

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• Lizz Maurais was selected as a recipient of the institutional CPRIT Training Grant. Congrats Lizz!

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April 2021

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• The lab received a 3-year grant from The Welch Foundation to study mechanisms of DNA repair. Thank you for supporting our research!

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• Jacob Sanders was awarded funding from the NCI T32 Training Grant in Cancer Biology. Congrats Jacob!

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• Qing and Rashmi's review article on the origins of genome rearrangements in cancer was published in Seminars in Cell & Developmental Biology. Congrats!

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January 2021

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• The year kicks off with new lab members: Welcome to postdoc Jacob Sanders and grad student Lizz Maurais. Lizz is the first graduate student of the Ly Lab!

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August 2020

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• The lab says farewell to Lizz Maurais, who joins the Ph.D. graduate program at UT Southwestern. Good luck Lizz!

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• Alison Guyer joins the lab as a research technician. Welcome Alison!

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April 2020

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• The lab receives two grant awards from the UTSW Kidney Cancer Program and the UTSW Circle of Friends. Thank you for supporting our work!

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March 2020

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• Yu-Fen Lin joins the lab as a senior research scientist. Welcome Yu-Fen!

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January 2020

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• Qing and Lizz's review covering methods to study genomic rearrangements is published in Chromosome Research. Congrats!

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October 2019

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• Rashmi Dahiya joins the lab as a postdoctoral fellow. Welcome Rashmi!​

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July 2019

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• Qing Hu joins the lab as a postdoctoral fellow and Elizabeth Maurais joins the lab as a research technician. Welcome Qing and Lizz!

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March 2019

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• Our paper linking mitotic errors to diverse forms of genome rearrangements is published in Nature Genetics!

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February 2019

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• The lab has officially opened at UTSW! ​

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• Our NIH R00 grant has been officially funded by the National Cancer Institute, providing three years of support for the lab.

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• Peter is selected as a Forbeck Scholar by the William Guy Forbeck Research Foundation. Learn more about the Foundation and the Scholars Program.​​

 

• The lab is awarded a CPRIT Scholar Recruitment Grant from the Cancer Prevention and Research Institute of Texas, providing five years of funding support. Click here for the official press release.